Estudios

Andrei M Darie. Fast multiplex bacterial PCR of bronchoalveolar lavage for antibiotic stewardship in hospitalised patients with pneumonia at risk of Gram-negative bacterial infection (Flagship II): a multicentre, randomised controlled trial. Lancet Respir Med 2022;10: 877–87 Interpretation Multiplex bacterial PCR examination of bronchoalveolar lavage decreases the duration of inappropriate antibiotic therapy of patients admitted to hospital with pneumonia and at risk of Gram-negative rod infection. This approach warrants further consideration in future antibiotic stewardship strategies.

Presenta Dr. Javier Riquelme

09 de agosto 2023 16:00hrs / 17:15hrs

Dupilumab for COPD with Type 2 Inflammation Indicated by Eosinophil Counts. N Engl J Med 2023;389:205-14. Among patients with COPD who had type 2 inflammation as indicated by elevated blood eosinophil counts, those who received dupilumab had fewer exacerbations, better lung function and quality of life, and less severe respiratory symptoms than those who received placebo.

Presenta Dr. Patricio Pérez

02 de agosto 2023 16:00hrs / 17:15hrs

Safety and effectiveness of bronchial thermoplasty after 10 years in patients with persistent asthma (BT10+): a follow-up of three randomised controlled trials. Lancet Respir Med 2021; 9: 457–66 Interpretation Our findings suggest that efficacy of bronchial thermoplasty is sustained for 10 years or more, with an acceptable safety profile. Therefore, bronchial thermoplasty is a long-acting therapeutic option for patients with asthma that remains uncontrolled despite optimised medical treatment.

Presenta Dra. María José Corrales

19 de julio 2023 16:00hrs / 17:15hrs

Evelijn S Lourijsen, Sietze Reitsma, Marleen Vleming et al. Endoscopic sinus surgery with medical therapy versus medical therapy for chronic rhinosinusitis with nasal polyps: a multicentre, randomised, controlled trial. Lancet Respir Med 2022; 10: 337–46

Presenta Dr. Felipe Cayupi

12 de julio 2023 16:00hrs / 17:15hrs

Segmentectomy versus lobectomy in small-sized peripheral non-small-cell lung cancer (JCOG0802/WJOG4607L): a multicentre, open-label, phase 3, randomised, controlled, non-inferiority trial. Lancet 2022; 399: 1607–17 The findings suggest that segmentectomy should be the standard surgical procedure for this population of patients.

Presenta Dr. Paulo Gnecco

05 de julio 2023 16:00hrs / 17:15hrs